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NAD+ Supplement for Cellular Aging


per bottle

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Target aging at the source—your cells. Increase your NAD+ levels with Basis for healthy aging, to boost cellular energy, and maintain healthy DNA. Developed by Elysium chief scientist and renowned aging researcher Leonard Guarente, Ph.D. Increase and sustain NAD+ levels by 40% to:

  • Promote healthy aging, feel good for your age
  • Promote cellular energy and reduce general tiredness and fatigue
  • Fight aging at the cellular level and protect your DNA from stressors
  • Support collagen and ceramide synthesis for healthy skin
  • Support healthy muscle function


    Basis contains two powerful ingredients to combat cellular aging:

    • Nicotinamide Riboside (NR-E)
NR is a naturally occurring form of vitamin B3 and a highly efficient precursor to NAD+—the raw material that the body uses to make NAD+ via a two-step process. This precursor has been shown to preferentially elevate NAD+ compared to nicotinic acid and nicotinamide, also called niacin.
    • Pterostilbene (PT)
A powerful polyphenol naturally produced by plants to protect against internal and external stress. The potent combination of NR and pterostilbene in Basis is designed to increase NAD+ levels and counter the decrease in the activity of sirtuins, which occurs with normal aging.
    • Vegetarian, vegan, gluten-free, nut-free, and contains no artificial colors or flavors.
    • NSF Certified for Sport, the only independent third-party certification program recognized by the United States Anti-Doping Agency (USADA). Please confirm the certification of each lot here.
    • See nutrition label for more information.
    • The quality and purity information of every lot is available here.

    Recommended Use

    • Take two capsules in the morning, with or without food.
    • Each bottle contains a 30-day supply.
    • This product is only intended for healthy adults. Do not take if you are pregnant or nursing. Consult with your physician before using.
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    Why NAD+ Is Essential

    First discovered in 1906, nicotinamide adenine dinucleotide, or NAD+, has become a prized molecule in recent years because of its central role in biological functions, the recent discovery that NAD+ levels decline in a wide variety of species (including humans) as they age, and its potential to positively affect human health through supplementation.

    Laboratory research in animals has found, among other things, that NAD+ is required for energy production, regulating our circadian rhythms, and maintaining DNA health. Elysium is working to translate this research to humans, beginning with our first clinical trial, published in November 2017.

    • Energy Creation

      NAD+ is a key player in making ATP, the source of energy in the cell.

    • Circadian Rhythm

      Our sleep and wake cycle, and everything it entails, depends on NAD+.

    • DNA Health

      We have several built-in systems for fixing errors in our DNA, and these systems need NAD+.

    Elysium’s Mission

    Elysium is a new kind of health company. Our mission is to solve the biggest challenges in health with science, to help people live healthier for longer. Working directly with the world’s leading scientists and clinicians, Elysium translates advances in science and technology into clinically-validated health products that work.

    Leonard Guarente, Chief Scientist

    Elysium was co-founded by Dr. Leonard Guarente, director of the Paul F. Glenn Center for Biology of Aging Research at MIT. Since 1982 Guarente has conducted research at MIT on the genetic and molecular basis of aging. As Elysium’s chief scientist, he steers the company's research and product development.

    Scientific Advisory Board

    Our Scientific Advisory Board is a network of more than 25 world-renowned researchers and clinicians, including Nobel Prize-winning scientists, who guide the direction of our company. They are experts in a broad range of subject matter, including biochemistry, neuroscience, and aging.

    This network of scientists advises the Elysium team on product identification and development, clinical studies, and ongoing research, accelerating the pace of discovery and ensuring a high level of scientific rigor in the development of Elysium’s products.

    Our Human Clinical Trial

    Basis is proven to increase NAD+ levels in the blood safely and sustainably. Our double-blind, randomized, placebo-controlled clinical trial, published in November 2017 in the peer-reviewed journal Nature Partner Journals: Aging and Mechanisms of Disease, demonstrated that Basis is proven to increase NAD+ levels in the blood by an average of 40 percent in adults taking the recommended daily dose.

    The increase was sustained throughout the duration of the trial. This is the first-ever demonstration that NAD+ levels can be increased and sustained in humans over a period of time.

    Frequently Asked Questions

    Why are sirtuins important for aging?

    Sirtuins are a family of proteins that regulate cellular health. Sirtuins play a key role in regulating cellular homeostasis. Homeostasis involves keeping the cell in balance. However, sirtuins can only function in the presence of NAD+, nicotinamide adenine dinucleotide, a coenzyme found in all living cells.

    How are the bi-monthly (every two months) delivery plans scheduled?

    Our bi-monthly plan has a thoughtfully-designed shipping schedule to ensure that you will never have a gap in your supply of Basis. For Canada orders, you will receive a two months supply with every shipment. The second shipment of this plan is processed 45-50 days after the first, so it arrives just before you are finished with the second bottle. After this, all future shipments are processed every 60 days. We can always make adjustments to your next shipment date at any time if you are developing a backlog or would like to pause for some time. Just contact us for help at

    Why can’t I add an additional subscription to my account?

    If you already have a subscription of your own and are looking to place an order for family or friends, you simply need to register a new account. This is so we can keep track of billing and shipping information, and ensure Basis is delivered on time to all of our customers. You can do this by logging out of your account, creating a new account, and setting a temporary password for the friend or family you are looking to send Basis to.

    Can I take Basis on top of my existing supplement routine?

    Please consult with your healthcare provider before taking Basis. Many of our customers take Basis along with their existing regimen of dietary supplements. We have identified no specific contraindications between Basis and other supplements.

    Can I take Basis with my prescription medications?

    We have identified no specific contraindications between Basis and prescription medications. Please consult with your healthcare provider before taking Basis to ensure that this view is confirmed by somebody who knows your medical history and can evaluate if Basis is right for you in the context of prescription medications.

    What is good health?

    Our health is ultimately determined by the health of the trillions of cells that make up our bodies. Inside each cell are components called organelles, including familiar names like the mitochondria and the nucleus, which work together, or “communicate,” to carry out all of the processes in our body. This communication doesn’t use words; it consists of physical, chemical, and nutritional processes by which cells convert food to energy, help our muscles move when we walk, and respond effectively when we get sick or injured. Generally speaking, healthy cells have everything they need to communicate well, while age and environmental factors like toxins and stress can lead to less than optimal health.

    What is the difference between healthspan and lifespan?

    Healthspan refers to the period of a time a person spends healthy and alive, while lifespan simply refers to the number of years a person lives. At Elysium, we emphasize the importance of healthspan because our goal is to help people live healthier lives.

    What should I do if I have not received my order?

    If you cannot locate your package, please contact us at and we will help you right away.

    Why do two bottles ship every two months for subscription plans?

    Shipping to Canada is more expensive than shipping within the U.S. We ship every two months to keep the costs down for our Canadian customers. Two bottles per shipment is the maximum we are legally permitted to send at one time; otherwise we would send more at once to reduce shipping costs further.